Figure 2From: How does endothelial cell injury start? The role of endothelin in systemic sclerosisSequence of pathological events leading to the development of SSc. ECM, extracellular matrix; IL, interleukin; PDGF, platelet-derived growth factor; SMC, smooth muscle cell; SSc, systemic sclerosis; TGF, transforming growth factor.Back to article page