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Table 3 Comparison of individual and domain neuropsychology test scores from the comprehensive battery between groups

From: Neuropsychological patterns in systemic lupus erythematosus patients with depression

Variable

Depressed-SLE patients (1)a

Depressed-Controls (2)a

Healthy Controls (3)a

P value

Post hoc analyses

Intelligence

45.5 ± 9.4

49.8 ± 6.9

51.5 ± 6.8

0.084

 

   WAIS-R Verbal IQ

47.2 ± 10.6

48.0 ± 8.1

49.8 ± 7.7

0.645

 

   WAIS-R Performance IQ

43.9 ± 10.3

51.5 ± 9.1

53.2 ± 7.7

0.012

1 < 3

Reasoning

45.7 ± 11.0

47.0 ± 5.6

55.7 ± 6.2

<0.001

1, 2 < 3

   WAIS-R Similarities

51.2 ± 9.6

48.6 ± 7.3

51.4 ± 9.6

0.703

 

   Category Test

46.8 ± 17.3

44.2 ± 6.6

52.2 ± 9.3

0.141

 

   Trail Making Test-Part A

42.1 ± 13.0

48.2 ± 9.7

61.2 ± 9.5

<0.0001

1, 2 < 3

Attention

41.8 ± 7.2

44.5 ± 5.4

50.0 ± 6.9

0.002

1 < 3

   Digit Vigilance Test-Time

44.7 ± 14.2

54.8 ± 11.9

54.8 ± 11.6

0.051

 

   Digit Vigilance Test-Errors

48.0 ± 11.9

38.1 ± 13.2

48.1 ± 12.0

0.085

 

   PASAT total

32.7 ± 15.7

41.7 ± 10.2

47.2 ± 9.0

0.002

1 < 3

Learning

42.0 ± 7.3

47.2 ± 6.6

47.5 ± 7.9

0.096

 

   Figure learning

41.5 ± 8.2

47.7 ± 10.3

46.7 ± 13.7

0.354

 

   Story learning

35.8 ± 6.8

47.6 ± 9.5

45.2 ± 9.2

0.003

1 < 3; 1 < 2

Recall

44.1 ± 7.6

49.1 ± 7.3

51.3 ± 7.2

0.021

1< 3

   Figure recall

48.8 ± 9.6

49.1 ± 9.3

53.8 ± 6.4

0. 120

 

   Story recall

39.3 ± 12.4

49.0 ± 9.2

48.9 ± 10.1

0.028

1< 2, 3

Fluency

49.5 ± 7.4

47.7 ± 4.1

48.2 ± 6.5

0.775

 

   Figural fluency

47.4 ± 10.4

44.9 ± 13.2

47.3 ± 8.8

0.814

 

Language

46.9 ± 6.3

51.2 ± 9.0

48.4 ± 7.0

0.378

 

   Oral-verbal comprehension

46.1 ± 9.3

51.2 ± 7.7

47.5 ± 7.9

0.327

 

   Written comprehension

47.8 ± 11.9

51.2 ± 13.6

49.4 ± 11.4

0.793

 

Perception

43.6 ± 11.5

52.8 ± 9.2

52.6 ± 7.4

0.017

1 < 3

   WAIS-R Block design

45.5 ± 11.7

51.0 ± 10.5

56.2 ± 10.2

0.018

1 < 3

   WAIS-R Object assembly

41.7 ± 12.3

54.5 ± 10.7

48.9 ± 7.6

0.011

1<2

  1. aData are presented as mean ± standard deviation. Depressed-Controls: control subjects with only a history or presence of major depressive disorder; Depressed-SLE: patients with a diagnosis of systemic lupus erythematosus and the presence of major depressive disorder; Figural fluency: Ruff Figural Fluency Test; Figure learning: Learning component of Figure Memory Test; Figure recall: Delayed component of Figure Memory Test; IQ: Intelligence Quotient; Letter fluency: Controlled Oral Word Association Test; Oral-verbal comprehension: Boston Diagnostic Aphasia Examination-Complex Ideational Material Test; PASAT: Paced Auditory Serial Addition Test; Story learning: Learning component of Story Memory Test; Story recall: Delayed component of Story Memory Test; WAIS-R: Wechsler Adult Intelligence Scale-Revised; Written comprehension: Peabody Individual Achievement Test reading recognition test.