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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice

Figure 4

Concentrations of interleukin-4 (IL-4) and interferon-γ (IFN-γ) in the supernatants of spleen cells harvested from mice with collagen-induced arthritis and treated with 1-methyl-tryptophan (1-MT) or vehicle. The release of IL-4 (a) and IFN-γ (b) into the supernatants of spleen cells in response to human or mouse type II collagen (CII) was determined at the end of the experiment. Values are presented as the mean and standard error of the mean of 16 animals per group (*p < 0.01).

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