Figure 5

Fc gamma receptor (FcγR) expression correlates with the presence of T cells in rheumatoid arthritis (RA) synovium. (a) Sequentially sectioned synovial tissue from a late stage RA patient demonstrating FcγRI, II and III positive cells perivasculary. The FcγR positive cells are located in the same area as CD3 positive T cells. Note the FcγRIII positive cell inside the vessel. This staining was representative of all other late RA synovial tissues stained in the same way (n = 26). The IgG1 isotype control did not show any background (data not shown). (Original magnification ×250.) (b) The expression of FcγRI, II and III was significantly correlated with the expression of CD3 in RA synovium (each symbol represents one patient, n = 26).