|
CT + TT genotype, n (%)
|
CC genotype, n (%)
|
Minor allele frequency
|
Cases versus all controlsa
|
---|
| | | |
χ2
|
P value
|
Pc value
|
Odds ratio
|
95% confidence interval
|
---|
Anti-CCP antibody-positive
|
113 (35.5)
|
205 (64.5)
|
0.196
|
24.99
|
0.0000006
|
0.0000024
|
2.01
|
1.51–2.67
|
Anti-CCP antibody-negative
|
40 (26.7)
|
110 (73.3)
|
0.145
|
1.97
|
0.16046
|
0.64184
|
1.32
|
0.88–2.00
|
Rheumatoid factor-positive
|
96 (36.4)
|
168 (63.6)
|
0.199
|
24.49
|
0.0000007
|
0.0000028
|
2.08
|
1.53–2.82
|
Rheumatoid factor-negative
|
28 (27.5)
|
74 (72.5)
|
0.142
|
1.87
|
0.17164
|
0.68656
|
1.38
|
0.85–2.23
|
- Pc, corrected P value. aControls presented in Table 2