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Table 4 Typical example of the direct versus the inferred assignment of one of the readers

From: Expert agreement confirms that negative changes in hand and foot radiographs are a surrogate for repair in patients with rheumatoid arthritis

Reader's direct judgement (direct assignment)

Reader's better/worse interpretation in combination with true time order of X-rays (inferred assignment):

Totals

 

Compatible with progression or no change

Compatible with repair

 

Progression/no change

21

15

36

Repair

1

27

28

Totals

22

42

64

  1. The inferred assignment is considered the gold standard. Direct assignment underestimates the true prevalence of repair. Percentage correctly classified, 75%; false direct assignment of repair, 1.5%; false direct assignment of progression, 23%; positive predictive value, 96%; negative predictive value, 58%.
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Arthritis Research & Therapy

ISSN: 1478-6362

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