Table 1 Patient characteristics at baseline: first versus fourth quartile based on cartilage volume loss
Global | Medial compartment | |||||
|---|---|---|---|---|---|---|
First quartile (greatest loss) (n = 27) | Fourth quartile (least loss) (n = 27) | P value | First quartile (greatest loss) (n = 27) | Fourth quartile (least loss) (n = 27) | P value | |
Age | 63.7 ± 7.2 | 61.3 ± 7.5 | 0.23 | 64.1 ± 7.4 | 61.6 ± 7.8 | 0.24 |
Female | 58% | 67% | 0.50 | 48% | 74% | 0.05 |
Weight (kg) | 84.9 ± 14.9 | 77.6 ± 14.3 | 0.07 | 86.3 ± 14.9 | 78.6 ± 16.3 | 0.07 |
Body mass index | 31.4 ± 3.9 | 29.1 ± 4.9 | 0.06 | 31.4 ± 3.6 | 29.6 ± 4.8 | 0.14 |
Joint space width (mm) | 2.84 ± 0.54 | 3.06 ± 0.64 | 0.18 | 2.70 ± 0.67 | 3.18 ± 0.66 | 0.01 |
WOMAC pain | 38.8 ± 22.1 | 35.4 ± 23.7 | 0.54 | 37.3 ± 23.2 | 34.1 ± 23.0 | 0.60 |
WOMAC function | 44.3 ± 23.3 | 38.0 ± 24.8 | 0.34 | 43.6 ± 23.9 | 37.2 ± 24.8 | 0.33 |
SF-36 | 39.0 ± 8.8 | 34.8 ± 9.8 | 0.10 | 40.2 ± 8.3 | 35.9 ± 8.4 | 0.07 |
Severe medial meniscal tear | 50% | 19% | 0.01 | 51% | 11% | 0.002 |
Medial meniscal tear | 85% | 81% | 0.76 | 92% | 66% | 0.02 |
Severe medial meniscal extrusion | 54% | 7% | 0.0001 | 56% | 7% | 0.0003 |
Medial meniscal extrusion | 81% | 52% | 0.02 | 82% | 48% | 0.01 |
Bone hypersignal | 77% | 48% | 0.03 | 81% | 37% | 0.002 |
Bone hypersignal in the medial compartment | 62% | 48% | 0.34 | 59% | 33% | 0.06 |
Bone hypersignal in the lateral compartment | 50% | 15% | 0.005 | 59% | 15% | 0.001 |