Table 2 Comparison of the baseline and the change in hand bone mineral density
Disease duration | DAS28 at baseline | MHAQ at baseline | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
≤3 years | >3 years | P value* | <3.2 | 3.2–5.1 | >5.1 | P value | <1.50 | 1.50–1.99 | ≥2.0 | P value | |
n | 37 | 178 | <0.01 | 55 | 103 | 44 | <0.01 | 102 | 78 | 34 | <0.01 |
Age (years) | 55.4 (43–62) | 58.0 (50–65) | 0.10 | 53.5 (39–61) | 55.8 (49–64) | 62.2 (57–67) | <0.01 | 53.6 (41–64) | 58.9 (52–64) | 61.2 (54–67) | <0.01 |
DXA-BMD (g/cm2) | 0.39 (0.34–0.43) | 0.36 (0.31–0.41) | 0.04 | 0.40 (0.36–0.43) | 0.38 (0.32–0.42) | 0.33 (0.28–0.38) | <0.01 | 0.38 (0.33–0.43) | 0.37 (0.31–0.41) | 0.34 (0.30–0.39) | 0.13 |
DXA-BMD change (%) | -0.96 (-4.4 to 1.5) | 0.24 (-1.4 to 2.1) | <0.01 | -0.40 (-2.4 to 1.8) | 0.26 (-1.3 to 2.2) | 0.04 (-3.4 to 2.2) | 0.40 | 0.11 (-2.5 to 2.1) | 0.0 (-1.2 to 2.0) | -0.12 (-4.1 to 2.2) | 0.75 |
DXR-BMD (g/cm2) | 0.57 (0.50–0.61) | 0.51 (0.44–0.56) | <0.01 | 0.56 (0.50–0.61) | 0.53 (0.45–0.58) | 0.46 (0.38–0.52) | <0.01 | 0.54 (0.49–0.59) | 0.49 (0.44–0.57) | 0.50 (0.40–0.53) | <0.01 |
DXR-BMD change (%) | -0.46 (-3.6 to 0.2) | -0.93 (-2.8 to 0.3) | 0.76 | -0.29 (-1.6 to 0.7) | -1.13 (-3.2 to 0.1) | -1.03 (-4.3 to 0.5) | 0.03 | -0.80 (-2.6 to 0.1) | -0.94 (-2.8 to 0.5) | -0.81 (-3.7 to 0.5) | 0.90 |
DXR-MCI | 0.40 (0.37–0.49) | 0.37 (0.31–0.45) | <0.01 | 0.41 (0.34–0.48) | 0.39 (0.33–0.46) | 0.32 (0.27–0.38) | <0.01 | 0.40 (0.33–0.48) | 0.37 (0.31–0.43) | 0.33 (0.29–0.41) | <0.01 |
DXR-MCI change (%) | -0.89 (-5.5 to 0.0) | -1.29 (-3.1 to -0.1) | 0.66 | -0.76 (-1.8 to 0.3) | -1.34 (-3.4 to -0.4) | -1.13 (-5.2 to -0.2) | 0.06 | -1.33 (-3.1 to -0.3) | -1.20 (-3.2 to 0.3) | -0.71 (-5.0 to 0.0) | 0.74 |