From: Skewed distribution of proinflammatory CD4+CD28nullT cells in rheumatoid arthritis
Patient | Gender, age (years) | Disease duration (years) | Treatmenta | Erosive disease | CD3+ in synovial membraneb | CD4+CD28null T cells | |||
---|---|---|---|---|---|---|---|---|---|
Peripheral blood (%) | Synovial fluid (%) | n/T-cell infiltratec | n/mm2 T-cell infiltratec | ||||||
>5% CD4+CD28null T cells in peripheral blood | |||||||||
1 | Female, 69 | 1 | P, M | - | ++ | 18 | 6 | 3 | 35 |
2 | Female, 45 | 15 | N, L | + | + | 9.8 | 10.4 | 2.5 | 54 |
3 | Female, 67 | 2.75 | N | + | ++ | 7.6 | 6.5 | 5 | 47 |
4 | Female, 51 | 33 | N, P | + | +++ | 13 | 1.5 | 4.7 | 48 |
5 | Male, 74 | 26 | N, P, E | + | ++ | 8.6 | 2.7 | 0.8 | 5 |
6 | Male, 38 | 22 | N, M, E | + | ++ | 8 | 0.8 | 2 | 39 |
<1% CD4+CD28null T cells in peripheral blood | |||||||||
7 | Male, 45 | 13 | N | + | + | 0 | 0.4 | 1.3 | 53 |
8 | Male, 25 | 0.6 | N, P, M | - | ++ | 0 | 0.2 | 3 | 51 |
9 | Female, 60 | Several years | N, D | - | ++ | 0 | 0.1 | 0 | 0 |
10 | Male, 41 | 1 | P | + | +++ | 0.4 | 0.8 | 4.5 | 67 |
11 | Female, 66 | 10 | M | + | ++ | 0.4 | 0.6 | 0 | 0 |