Association of the microsatellite in the 3' untranslated region of the CD154 gene with rheumatoid arthritis in females from a Spanish cohort: a case-control study

Table 3 Basal expression of surface markers in PBMCs of patients with RA according to CD154 genotype

Surface markers	24CAs (n = 13)	Non-24CAs (n = 15)	P
CD16/CD56^a	16.07 ± 10.78	12.38 ± 10.24	n.s.
CD19^a	6.42 ± 3.12	4.17 ± 3.01	0.018
CD3/CD8^a	17.24 ± 7.66	22.37 ± 6.67	n.s.
CD3/CD4^a	44.40 ± 14.79	41.22 ± 13.11	n.s.
CD4/CD69^b	14.09 ± 19.02	7.48 ± 10.25	n.s.
CD4/CD25^b	59.59 ± 18.04	41.19 ± 22.84	0.036
CD4/CD154^b	4.28 ± 3.81	8.12 ± 5.73	0.033

Results are means ± SD for cells expressing the indicated surface markers, quantified by flow cytometry. Differences were evaluated by the Mann–Whitney U test. n, number of samples analyzed; n.s., non significant; PBMCs, peripheral blood mononuclear cells. ^aReferred to total lymphocytes; ^breferred to total CD4⁺ lymphocytes.

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