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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Src kinase inhibition promotes the chondrocyte phenotype

Figure 1

Expression of Src kinases in chondrogenic cells. Expression of (a) Lyn, (b) Frk and (c) Hck Src kinase genes during chondrogenic differentiation of ATDC5 cells (days 3 to 18) was analyzed using Taqman real-time PCR analyses. Lyn mRNA levels increased strongly during differentiation, whereas the other two kinase genes exhibited more subtle changes in gene expression. (d) Western blotting confirmed expression of Lyn protein in primary mouse chondrocytes in monolayer culture for 1 to 3 days.

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