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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Src kinase inhibition promotes the chondrocyte phenotype

Figure 4

PP2 promotes expression of genes involved in glycosaminoglycan synthesis. Primary mouse chondrocytes were incubated for 1 to 3 days with dimethyl sulphoxide or the Src inhibitor PP2 (10 ╬╝mol/l), and transcript levels of genes involved in glycosaminoglycan synthesis were determined by real-time PCR. Expression levels of (a) Xylt1, (b) Xylt2, (c) Chst3 and (d) Chst11 were significantly increased upon Src inhibition (n = 3; *P < 0.05).

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