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Table 3 Imbalance of baseline measures of standardized cartilage biomarkers and prediction of subsequent cartilage loss on magnetic resonance imaging

From: Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study

  Unadjusted OR (95% CI) R 2 AUC P value Adjusted ORa (95% CI)
CTX/CPII 0.72 (0.03, 16.66) 0.001 0.52 0.84 0.53 (0.02, 13.23)
C2C/CPII <0.001 (<0.001, 1.14) 0.04 0.60 0.05 0.001 (<0.001, 1.46)
C1,2C/CPII 0.24 (0.002, 39.12) 0.003 0.52 0.59 0.31 (0.002, 52.18)
C1,2C/C2C 0.19 (0.02, 2.12) 0.02 0.57 0.18 0.22 (0.02, 2.48)
Col2CTX/Cr ratio/C2C 1.60 (0.31, 8.19) 0.003 0.52 0.57 1.37 (0.26, 7.40)
  1. aAdjusted for age, gender, and body mass index. AUC, area under the curve; C2C, collagenase cleavage of triple-helical type II collagen; CI, confidence interval; Col2CTx, Crosslinked peptides from the C-telopeptide domain of type II collagen; CPII, C-propeptide of type II collagen; OR, odds ratio.