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Table 3 Imbalance of baseline measures of standardized cartilage biomarkers and prediction of subsequent cartilage loss on magnetic resonance imaging

From: Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study

 

Unadjusted OR (95% CI)

R 2

AUC

P value

Adjusted ORa (95% CI)

CTX/CPII

0.72 (0.03, 16.66)

0.001

0.52

0.84

0.53 (0.02, 13.23)

C2C/CPII

<0.001 (<0.001, 1.14)

0.04

0.60

0.05

0.001 (<0.001, 1.46)

C1,2C/CPII

0.24 (0.002, 39.12)

0.003

0.52

0.59

0.31 (0.002, 52.18)

C1,2C/C2C

0.19 (0.02, 2.12)

0.02

0.57

0.18

0.22 (0.02, 2.48)

Col2CTX/Cr ratio/C2C

1.60 (0.31, 8.19)

0.003

0.52

0.57

1.37 (0.26, 7.40)

  1. aAdjusted for age, gender, and body mass index. AUC, area under the curve; C2C, collagenase cleavage of triple-helical type II collagen; CI, confidence interval; Col2CTx, Crosslinked peptides from the C-telopeptide domain of type II collagen; CPII, C-propeptide of type II collagen; OR, odds ratio.