Placebo | 25 mg | 50 mg | 100 mg | 200 mg | |
---|---|---|---|---|---|
Patients with hand adverse events, number (percentage) | 5/77 (6%) | 8/80 (10%) | 9/79 (11%) | 7/80 (9%) | 23/79 (29%) |
Patients with particular hand findings (hand oedema overlapped with other findings), number | |||||
Hand oedema | 0 | 0 | 1 | 1 | 3 |
Palmar fibrosis | 0 | 1 | 1 | 2 | 12 |
Dupuytren contracture | 0 | 1 | 0 | 3 | 1 |
Tendon thickness/nodules | 0 | 0 | 0 | 0 | 2 |
Symptomatic patients, number | 0 | 0 | 1 | 2 | 4 |