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Table 3 Comparison of single-nucleotide polymorphisms and Fibromyalgia Impact Questionnaire scores in patients from Mexico and Spain

From: Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia

 

Spaniards

Mexicans

Genotypes

25th percentile

Median

75th percentile

P value

25th percentile

Median

75th percentile

P value

rs6269

        

   AA

75.1

78.6

82.1

 

57.7

67.53

80.5

 

   AG

60.6

67.1

70.1

0.0001

68.7

77.5

80.67

0.193

   GG

51.1

56.3

56.7

 

41.01

66.77

79.17

 

rs4633

        

   CC

73.9

78.7

86.1

 

61.4

71.25

78.17

 

   CT

59.8

62.6

68.5

0.0001

60.7

71.29

82.7

0.785

   TT

51.1

56.2

56.7

 

57.7

66.21

85.47

 

rs4818

        

   CC

75.1

78.1

82.4

 

57.7

64.20

80.5

 

   GC

60.2

65.3

70.2

0.0001

68.74

77.5

81.58

0.054

   GG

51.7

56.2

61.7

 

60.43

66.33

73.17

 

rs4680

        

   AA

50.62

52.3

56.1

 

57.7

72.97

88.24

 

   AG

59.4

62.1

68.3

0.0001

62.7

74.35

83.60

0.284

   GG

72.8

78.6

85

 

59.9

68.74

76.46

 
  1. Only single-nucleotide polymorphisms with significant associations in Spaniards are shown. In Mexicans, none was associated with the Fibromyalgia Impact Questionnaire.