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Table 2 Weighted mean daily faecal blood loss by therapy

From: Faecal blood loss with aspirin, nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 selective inhibitors: systematic review of randomized trials using autologous chromium-labelled erythrocytes

Treatment/drug Studies or study arms (n) Participants (n) Weighted mean faecal blood loss (ml/day)
Initial blood loss at start of trial 38 950 0.46
Placebo arm of treatment 14 172 0.76
Aspirin (>1,800 mg/day) 29 361 5.01
Aspirin (325 mg/day) 4 64 1.61
Ibuprofen 4 66 2.03
Fenoprofen 4 62 1.86
Piroxicam 6 60 1.89
Naproxen 4 59 1.98
Indomethacin 6 58 1.39
Etodolac 4 39 0.55
Rofecoxib 1 37 0.80
Diflusinal 4 33 1.68
Ketoprofen 3 28 1.42
Meloxicam 1 26 0.85
Etoricoxib 1 21 0.90
Diclofenac 1 21 0.50
Azapropazone 2 20 1.00
Suoprofen 1 20 1.80
Nefopam 1 19 0.60
Tiaprofen 2 17 0.51
Zomepirac 2 16 6.40
Oxindanac 1 16 1.30
Sulindac 2 15 0.75
Lornoxicam 1 15 0.80
Bromfenac 1 12 2.10
Fluproquazone 1 12 2.80
Nabumetone 1 10 1.60
Oxaprozin 1 10 2.30
Isoxicam 1 8 1.00
Ticlotil 1 8 2.10
Tenoxicam 1 6 1.20
Flurbiprofen 1 6 1.30
  1. Note that all low dose aspirin was 325 mg/day.