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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model

Figure 3

Indoleamine 2,3-dioxygenase-expressing CD11c+ dendritic cells display a phenotype consistent with the immature state. Indoleamine 2,3-dioxygenase (IDO)+CD11c+ dendritic cells (DCs) were stained for markers of DC maturity and were analyzed using three-color flow cytometry. Mononuclear cells from Peyer's patches were stained for CD11c, IDO, and Major Histocompatibility Complex (MHC) II, or costimulatory molecule markers. All plots were first gated on IDO+CD11c+ cells. Dotted line shows the isotype-matched controls. Data are the mean ± standard deviation of three experiments. MFI, mean fluorescence index.

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