Table 2 Strain membership-prediction potential of individual biomarkers
R* | Specificity | Sensitivity | Hit rate | |
|---|---|---|---|---|
Salivary flow | 0.849 | 100% | 100% | 100% |
Serum | ||||
IgA | 0.921 | 100% | 100% | 100% |
Anti-M3R IgG2c | 0.902 | 92% | 100% | 96% |
Cystatin-C | 0.856 | 83% | 92% | 88% |
Insulin | 0.837 | 92% | 83% | 88% |
CRP | 0.812 | 92% | 92% | 92% |
MIP-1γ (CCL-9) | 0.784 | 100% | 92% | 96% |
VCAM-1 | 0.783 | 92% | 92% | 92% |
OPN (SSP-1) | 0.778 | 83% | 92% | 88% |
SAP | 0.757 | 92% | 83% | 88% |
Fibrinogen | 0.747 | 83% | 100% | 92% |
MPO | 0.708 | 75% | 92% | 83% |
Growth hormone | 0.703 | 67% | 100% | 83% |
MDC (CCL-22) | 0.693 | 75% | 92% | 83% |
IL-1α | 0.678 | 83% | 83% | 83% |
MIP-3β (CCL-19) | 0.665 | 92% | 92% | 92% |
IL-18 | 0.653 | 75% | 100% | 88% |
MCP-3 (CCL-7) | 0.648 | 67% | 92% | 79% |
CD40 | 0.645 | 67% | 92% | 79% |
MCP-1 (CCL-2) | 0.643 | 67% | 100% | 83% |
Anti-M3R IgG2b | 0.600 | 67% | 100% | 83% |
Saliva | ||||
RANTES (CCL-5) | 0.799 | 75% | 92% | 83% |
GCP-2 (CXCL-5) | 0.745 | 75% | 92% | 83% |
IP-10 (CXCL-10) | 0.731 | 75% | 100% | 88% |
TPO | 0.678 | 67% | 83% | 75% |
Anti-SCL70 | 0.645 | 50% | 100% | 80% |
IL-11 | 0.603 | 58% | 92% | 75% |