Table 1 Genotype and allele frequencies of A/G transition SNP (rs585017) of the RHOB gene in Chinese and Japanese populations
Group | Number of individuals | Genotype count (frequency) | Â | Allele count (frequency) | ||
|---|---|---|---|---|---|---|
| Â | Â | AA | AG | GG | A | G |
Chinese patients with knee OA | ||||||
   All | 469 | 434 (0.925) | 35 (0.075) | 0 | 903(0.963) | 35 (0.037) |
   Female | 323 | 303 (0.938) | 20 (0.062) | 0 | 626 (0.969) | 20 (0.031) |
   Male | 146 | 131 (0.897) | 15 (0.103) | 0 | 277 (0.949) | 15 (0.051) |
Chinese control individuals | ||||||
   All | 486 | 460(0.947) | 26 (0.053) | 0 | 946 (0.973) | 26 (0.027) |
   Female | 316 | 296 (0.937) | 20 (0.063) | 0 | 612 (0.968) | 20 (0.032) |
   Male | 170 | 164 (0.965) | 6 (0.035) | 0 | 334 (0.982) | 6 (0.018) |
Japanese patients with knee OA | ||||||
   All | 376 | 350 (0.931) | 26 (0.069) | 0 | 726 (0.965) | 26 (0.035) |
   Female | 327 | 303 (0.927) | 24 (0.073) | 0 | 630 (0.963) | 24 (0.037) |
   Male | 49 | 47 (0.959) | 2 (0.041) | 0 | 96 (0.980) | 2 (0.020) |
Japanese control individuals | ||||||
   All | 371 | 343 (0.925) | 28 (0.075) | 0 | 714 (0.962) | 28 (0.038) |
   Female | 113 | 103 (0.912) | 10 (0.088) | 0 | 216 (0.956) | 10 (0.044) |
   Male | 258 | 240 (0.930) | 18 (0.070) | 0 | 498 (0.965) | 18 (0.035) |