Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis

Table 5 Meta-analysis: summary of association and heterogeneity of the TXNDC3 C/T polymorphism in knee osteoarthritis

Study	CC+CT versus TT				CC versus CT+TT				C allele versus T allele
	Summary			Heterogeneity	Summary			Heterogeneity	Summary			Heterogeneity
	OR	95% CI	P	P	OR	95% CI	P	P	OR	95% CI	P	P
All	1	0.47–2.16	0.99	0.09	1.35	0.93–1.96	0.11	0.01	1.21	0.95–1.53	0.12	0.07
Replication	1.13	0.38–3.34	0.82	0.053	1.14	0.89–1.47	0.29	0.14	1.14	0.90–1.43	0.28	0.11
Asian	1.15	0.1–12.92	0.91	0.02	1.32	1.03–1.67	0.03	0.97	1.29	1.03–1.61	0.02	0.51

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