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Table 2 Cross-sectional associations at baseline between NT-proBNP (dependent variable) and rheumatoid arthritis disease activity

From: The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study

  Adjusted linear regression Multivariate linear regression
  β coefficient P value β coefficient P value
Age 1.02 (1.01–1.03) < 0.001 1.009 (1.00–1.02) 0.04
Male gender 0.74 (0.59–0.95) 0.02 0.10 (0.04–0.23) < 0.001
C-reactive proteina 1.01 (1.01–1.02) 0.002 1.01 (1.01–1.02) 0.001
RF IgM-positivea, b 0.96 (0.79–1.17) 0.67   
Anti-CCP-positivea, b 0.90 (0.74–1.10) 0.30   
Gluocorticoid usera, b 1.17 (0.94–1.48) 0.16   
DMARD usera, b 1.04 (0.85–1.26) 0.71   
NSAID usera, b 0.97 (0.80–1.19) 0.81   
Ritchie scorea 1.01 (0.99–1.03) 0.21   
HAQa 1.06 (0.90–1.24) 0.47   
Sharp scorea 1.00 (0.99–1.02) 0.93   
Disease durationa 0.99 (0.91–1.08) 0.82   
Age × male gender    1.04 (1.02–1.05) < 0.001
R2 adjusted    0.23 < 0.05
  1. aAge- and gender-adjusted; bdichotomized variable. anti-CCP, anti-cyclic citrullinated peptide antibody; DMARD, disease-modifying anti-rheumatic drug; HAQ, Stanford Health Assessment Questionnaire; NSAID, non-steroidal anti-inflammatory drug; NT-proBNP, N-terminal pro-brain natriuretic peptide; RF, rheumatoid factor; Ritchie score, Ritchie articular index; Sharp score, van der Heijde modified Sharp criteria.
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