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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis

Figure 2

Vascular endothelial mediators and their effects. Adapted with permission from Lüscher and Barton [115]. Ang, angiotensin; bFGF, basic fibroblast growth factor; ET, endothelin; ETA/B, endothelin receptor subtype A/B; ICAM, intracytoplasmic adhesion molecule; IL, interleukin; LDL, low-density lipoprotein; oxLDL, oxidized low-density lipoprotein; MCP, monocyte chemoattractant protein; NO, nitric oxide; NOS, nitric oxide synthase; O2-, superoxide; ONOO-, peroxynitrite; PAI, plasminogen activator inhibitor; PDGF, platelet derived growth factor; TGF, transforming growth factor; TNF, tumor necrosis factor; VCAM, vascular cell adhesion molecule.

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