Figure 2

Severity of collagen-induced arthritis in Cia40 congenic male and female mice. (a) Mean (standard error, SE) arthritic scores in homozygous Cia40 congenic females, heterozygous Cia40 congenic females, and wildtype littermate females. Only mice that developed arthritis have been included. Heterozygous congenic females show higher severity than wildtype B10.Q and congenic homozygous females (P < 0.05). (b) Mean (SE) arthritic scores in homozygous Cia40 congenic males, heterozygous Cia40 congenic males, and wildtype littermate males. Only mice that developed arthritis have been included. Heterozygous congenic males show significantly higher severity than wildtype B10.Q littermates (P < 0.05).