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Table 2 BOKS analysis: independent association of standardized biomarkers with BML (BML > 0) per SD of change in marker

From: Biochemical markers of bone turnover and their association with bone marrow lesions

   

Univariate association

Full model (including age, sex and BMI)

 

Marker

(BML = 0)

(BML > 0)

OR

95% CI

R2

Full model R2

Full model ROC area

Ln-BSAP

3.48 (0.35)

3.57 (0.36)

1.4

(0. 9, 2.0)

2.58

14.56

0.701

Ln-osteocalcin

2.73 (0.51)

2.80 (0.55)

1.2

(0.8, 1.7)

0.8

13.41

0.687

Ln-NTx

-3.47 (1.07)

-3.27 (0.78)

1.4

(1.0, 2.0)

3.05

14.55

0.697

  1. BMI, body mass index; BML, bone marrow; BOKS, Boston Osteoarthritis Knee Study; BSAP, bone-specific alkaline phosphatase; Ln, Natural Log; NTx, type I collagen N-telopeptide; SD, standard deviation.