Figure 2

Serotonin-induced platelet aggregation in subjects with the ⁴⁵²His/⁴⁵²His or the ⁴⁵²His/⁴⁵²Tyr phenotype. Fold increase of serotonin (5-HT)-induced platelet aggregation after correction for baseline ADP aggregation values by the weighted least-squares analysis procedure (see Materials and methods) in subjects with the ⁴⁵²His/⁴⁵²His or the ⁴⁵²His/⁴⁵²Tyr phenotype. Black centre line, median for each dataset; boxes, interquartile range; bars, cases (three box-lengths form the 25th or the 75th percentile).