Table 2 Gastrointestinal risk of non-steroidal anti-inflammatory drugs/cyclooxygenase-2 from safest to riskiest
From: Developments in the clinical understanding of osteoarthritis
Safer | Nonacetylated salicylates (for example, salsalate) |
| Â | Nabumetone |
| Â | Celecoxib |
| Â | Ibuprofen |
↓ | Diclofenac |
| Â | Sulindac |
| Â | Naproxen |
| Â | Indomethacin |
Riskier | Ketoprofen |