Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study

Table 1 Genotype and allele frequencies of C/T transition SNP (rs143383) of the GDF5 gene in the Han Chinese population.

Group	Number of subject	Genotype (frequency)			Allele (frequency)		Hardy-Weinberg equilibrium
		TT	TC	CC	T	C	P value
CDH
All	338	214 (0.633)	111 (0.328)	13 (0.039)	539 (0.797)	137 (0.203)	0.77
Female	291	185 (0.636)	95 (0.326)	11 (0.038)	465 (0.799)	117 (0.201)	0.78
Male	47	29 (0.617)	16 (0.340)	2 (0.043)	74 (0.787)	20 (0.213)	0.91
Control
All	622	342 (0.550)	234 (0.376)	46 (0.074)	918 (0.738)	326 (0.262)	0.50
Female	316	169 (0.535)	124 (0.392)	23 (0.073)	462 (0.731)	170 (0.269)	0.97
Male	306	173 (0.565)	110 (0.360)	23 (0.075)	456 (0.745)	156 (0.255)	0.35

CDH = congenital dysplasia of the hip; GDF5 = growth differentiate factor 5; SNP = single nucleotide polymorphism.

ISSN: 1478-6362