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Table 3 Synthetic peptides for screening T cell epitopes

From: Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis

Peptide number Peptide Synthetic peptide sequence
1 1–20 H-MAA LT R DP Q FQKLQQWYREH-OH
2 23–42 H-ELNLRRL FD A NK D RFNHFSL-OH
3 37–56 H-FNHFS LT L NT N HGHILVDYS-OH
4 51–70 H-ILVDYS KN L VT E DVMRMLVD-OH
5 71–90 H-LA KS R GV E A A RE R MF N GEKI-OH
6 96–115 H-RAVL HV A LR N RS N TPILVDG-OH
7 145–164 H-TGKTI TD V IN I GIGGSDLGP-OH
8 162–181 H-LGPLMV TE A LK P YSSGGPRV-OH
9 168–187 H-TEALKP YS S GG P RVWYVSNI-OH
10 176–195 H-SGGPRV WY V SN I DGTHIAKT-OH
11 191–210 H-HIAKTL AQ L NP E SSLFIIAS-OH
12 200–219 H-NP ES S LF I IA S KT F TT Q ETI-OH
13 225–244 H-AKEWFL Q AA K DP SAVAKHFV-OH
14 238–257 H-AVAKHF VA L ST N TTKVKEFG-OH
15 247–266 H-STNTTKV KE F GI D PQNMFEF-OH
16 280–299 H-IGLSIA LH V GF D NFEQLLSG-OH
17 313–332 H-EKNAPVL LA L LG I WYINCFG-OH
18 327–346 H-YI NC F GC E TH A ML P YD Q YLH-OH
19 386–405 H-NGQHAF YQ L IH Q GTKMIPCD-OH
20 400–419 H-KMIP CD FL I PV QT Q HPIRKG-OH
21 420–439 H-LHHKILL AN F LA Q TEALMRG-OH
22 445–464 H-ARKELQAA GK S PE D LERLLP-OH
23 484–503 H-PFMLGA LV A MY E HKIFVQGI-OH
24 533–552 H-AQVTS HD A ST N GL I NFIKQQ-OH
25 539–558 H-DASTNGL IN F IK Q QREARVQ-OH
  1. Listed are 25 20-mer unpurified peptides in which each core sequence were centred around. Amino acid residues constituting the core sequence and those thought to bind anchors of I-Aq are underlined and shown in bold letters, respectively.