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Table 4 Re-synthesised peptides used for determining a major epitope

From: Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis

Peptide number Peptide Synthetic peptide sequence
18 327–346 H-YI NC F GC E TH A ML P YD Q YLH-OH
  325–339 H-IWYI NC F GC E THAML-OH
  334–348 H-ETHA ML P YD Q YLHRF-OH
25 539–558 H-DASTNGL IN F IK Q QREARVQ-OH
  542–556   H-TNGL IN F IK Q QREAR-OH
  544–558           H-GL IN F IK Q QREARVQ-OH
  1. The 15-mer peptides were synthesised with 90% purity, containing each core sequence of number 18 peptide (GPI327–346) and number 25 peptide (GPI539–558). Amino acid residues constituting the core sequence and those thought to bind the anchors of I-Aq are underlined and shown in bold letters, respectively.