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Table 1 Sensitivity of LIA, ELISA, EliA® Rib-P, IB, and IIF versus ALBIA

From: Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies

   All Mediuma + high MFU Only highb MFU
   n = 51 n = 27 n = 20
LIA Positive + borderline, number (percentage) 19 (37.3) 9 (33.3) 7 (35.0)
  Positive, number (percentage) 13 (25.5) 8 (29.6) 7 (35.0)
ELISA Positive + borderline, number (percentage) 36 (70.6) 21 (77.8) 14 (70.0)
  Positive, number (percentage) 27 (52.9) 17 (63.0) 12 (60.0)
EliA® Positive + borderline, number (percentage) 22 (43.1) 12 (44.4) 8 (40.0)
  Positive, number (percentage) 21 (41.2) 11 (40.7) 8 (40.0)
IIF (CSP) Positive, number (percentage) 14 (27.5) 11 (40.7) 8 (40.0)
IB At least one Rib-P band, number (percentage) 20 (39.2) 10 (37.0) 7 (35.0)
  1. aMedium 50 to 100 median fluorescence units (MFU); bhigh ≥ 100 MFU. ALBIA, addressable laser bead immunoassay; CSP, cytoplasmic staining pattern; ELISA, enzyme-linked immunosorbent assay; IB, immunoblot; IIF, indirect immunofluorescence; LIA, line immunoassay; Rib-P, ribosomal P protein.