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Figure 6 | Arthritis Research & Therapy

Figure 6

From: Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGFβ-1 in cultured rat nucleus pulposus cells

Figure 6

Effects of inhibitors and transforming growth factor β1 (TGFβ1) on cell cycle progression. Serum-deprived nucleus pulposus cells were treated with or without inhibitors (16 μM 10058-F4, or 30 μM PD98059) then treated with 5 or 20 ng/mL TGFβ1 for 24 h. The percentage of cells in S-phase was determined with fluorescence-activated cell sorting (FACS). Black bar, white bar and gray bar indicate the results obtained for three rats respectively. (*p < 0.05)

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