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Table 3 Comparison of the number of serious NSAID ulcer complications and associated costs in the two extrapolations (all using PPIs vs none using PPIs)

From: Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study

 

No PPI users

(n = 1,000)

PPI users

(n = 1,000)

Difference

No. of complications (95% CI)

13.8 (13.7 to 13.9)

3.60 (3.56 to 3.64)

10.2

Costsa (95% CI)

€ 115,676 (114,874 to 116,493)

€ 165,770 (160,789 to 173,444)

€ 50,094

  1. aCost of cheapest concomitant PPI (generic omeprazole) was taken into account. NSAID, non-steroidal anti-inflammatory drug; PPI, proton pump inhibitor.