Skip to main content

Advertisement

Table 1 Comparison of SNPs in the present study with the literature (Reference SNP (rs) and PCR primers)

From: No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis

PubMed identifier Gene SNP reference Allele MAFa Found in the literature? PCR primers
Present study TLR1 rs5743618 G/T   No Forward, 5'-CCCGGAAAGTTATAGAGGAACCCT-3'
       Reverse, 5'-TTCACCCAGAAAGAATCGTGCCCA-3'
Present study   rs5743594 C/T   No Forward, 5'-AAGATCAGGGTGGTAGTGTTGG-3'
       Reverse, 5'-CCCAATTCTTCCTCTCCAGCTT-3'
Present study TLR2 rs3804099 C/T   No Forward, 5'-ATCGTCTTCCTGGTTCAAGC-3'
       Reverse, 5'-CAGTTCCAAACATTCCACGG-3'
Present study   rs4696480 T/A   No Forward, 5'-CAAATTTAAAAGAGGGCAAGAAA-3'
       Reverse, 5'-CAGTTTATTGTGAGAATGAGTTT-3'
Present study TLR4 rs2737191 A/G   No Forward, 5'-CATCCCCTACTTTCTTCACA-3'
       Reverse, 5'-TCAACTCAGGACCCATAATC-3'
Present study   rs4986790 A/G 32%/32.50% Yes: other name Asp299Gly Forward, 5'-TCTGGGAGAATTTAGAAATGAA-3'
       Reverse, 5'-AAACGTATCCAATGAAAAGAAG-3'
Present study   rs1554973 T/C   No Forward, 5'-CAAAGGATATGTGAACAATAGG-3'
       Reverse, 5'-AATCCCGTGAGTAGAGAATG-3'
Present study TLR6 rs5743810 C/T   No Forward, 5'-ACTTGGTTCGTGATATGTTCTA-3'
       Reverse, 5'-AAACCCTTCACCTTGTTTTTCA-3'
Present study TLR9 rs187084 C/T   No Forward, 5'-TCTGGGACAAGTCCAGCCAG-3'
       Reverse, 5'-GGACACTCCCAGCTCTGAAG-3'
Present study   rs352140 T/C   No Forward, 5'-CTGCTAGCACACCGGATCAT-3'
       Reverse, 5'-ATGATACCACCCAGAGTGGG-3'
  1. aMutation allele frequency, presented as cases/controls.