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Table 5 Transmission disequilibrium test in rheumatoid arthritis families with RF, anti-CCP antibody, or joint erosions

From: No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis

   RF Anti-CCP antibody Erosions
Gene SNP reference Transmitted/untransmitted P value Transmitted/untransmitted P value Transmitted/untransmitted P value
TLR1 rs5743618 (+7765 S602I) 33/28 0.52 34/29 0.53 32/32 1
  rs5743594 (+3663) 15/22 0.25 14/20 0.3 20/21 0.88
TLR2 rs3804099 (+15591 N199N) 39/40 0.91 41/36 0.57 47/39 0.39
  rs4696480 (-1938) 46/39 0.45 41/44 0.74 42/48 0.53
TLR4 rs2737191 (-3869) 38/35 0.73 33/36 0.72 38/42 0.65
  rs4986790 (+8719 D259G) 7/9 0.62 9/12 0.51 10/11 0.83
  rs1554973 (+14229) 30/30 1 25/25 1 32/31 0.9
TLR6 rs5743810 (+744 S249P) 48/41 0.46 48/44 0.68 51/49 0.84
TLR9 rs187084 (+3483 P545P) 37/35 0.81 38/35 0.73 40/39 0.91
  rs352140 (-851) 36/37 0.91 34/36 0.81 37/35 0.81
  1. RF, rheumatoid factor; anti-CCP, anti-cyclic citrullinated peptide.