Figure 1
From: The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease
Overview of the surgical procedures used to generate meniscotibial transection (MTX) and partial meniscoectomy (PMX) models. (a) Schematic representation of the joint (Adapted from Kamekura and colleagues [34]). (b) An incision through the skin and subcutaneous tissue exposes the stifle joint. Prominent features include the medial collateral ligament (MCL), the patellar ligament and the tibial tuberosity. (c) The joint capsule has been cut on the medial side of the joint and the patella has been reflected laterally. This exposes the internal structures of the joint. Prominent features include the medial femoral chondyle (MFC), the medial meniscus (MM), the meniscotibial ligament (MTL) and the anterior cruciate ligament (ACL). (d) The MTL has been cut to release the MM. (e) The partial meniscectomy has been completed and the cut edge of the MM can be seen. Note that in order to visualise the cut edge of the meniscus, for pictorial purposes, the anterior cruciate ligament (ACL) has been transected. LM, lateral meniscus.