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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent

Figure 4

Surface expression of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors on rheumatoid arthritis synovial fibroblasts (RASFs). (a) Staining of TRAIL receptors, as analysed by flow cytometry, showed constitutive surface expression of TRAIL-R1 and TRAIL-R2 on RASFs in vitro. TRAIL-R3 and TRAIL-R4 were not detectable. The expression levels did not change in confluent RASFs. (b) Furthermore, cell surface expression of TRAIL-R1 and TRAIL-R3 on RASFs remained unchanged in RASFs synchronised with hydroxyurea (HU). Representative histograms of three separate experiments are shown.

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Arthritis Research & Therapy

ISSN: 1478-6362

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