Figure 5
From: In vitromodel for the analysis of synovial fibroblast-mediated degradation of intact cartilage
Invasion of cartilage by synovial fibroblasts (SFB) after six weeks of co-culture (Light microscopy). An initial invasion of SFB into superficial cartilage areas was observed in (b) TNF-α/IL-1β co-stimulated samples, but not in the case of (a) non-stimulated samples and samples stimulated with TNF-α or IL-1β alone (data not shown). Magnifications in (a) and (b) 400×; inserts 100×.