Table 1 Patient characteristics
Total | Missing data | Limited cutaneous systemic sclerosis | Diffuse cutaneous systemic sclerosis | Overlap syndrome | |
|---|---|---|---|---|---|
Characteristic | |||||
Number of patients (n (%)) | 1,419 (100%) | 0.9 | 56 (53.4%) | 492 (34.7%) | 168 (11.9%) |
Female | 82.8 | 0.1 | 88.0 | 74.9 | 85.1 |
Male | 17.2 | 0.1 | 12.0 | 25.1 | 14.9 |
Antinuclear antibodies (ANA)-positive | 91.5 | 0.5 | 89.9 | 91.9 | 95.8 |
Scl 70-positive | 30.9 | 0.7 | 18.5 | 55.6 | 11.4 |
Anticentromere antibodies (ACA)-positive | 36.6 | 2.5 | 59.7 | 10.2 | 16.2 |
Organ involvement by systemic sclerosis subset | |||||
Raynaud phenomenon | 95.8 | 0.2 | 96.3 | 95.1 | 96.4 |
Skin involvement | 93.5 | 0.4 | 92.8 | 97.5 | 83.9 |
Pulmonary hypertension | 14.2 | 0.4 | 12.8 | 17.7 | 9.5 |
Pulmonary fibrosis | 38.0 | 0.4 | 24.6 | 59.1 | 33.3 |
Esophagus | 63.6 | 0.3 | 61.1 | 67.4 | 64.9 |
Stomach | 15.2 | 0.5 | 15.8 | 14.5 | 14.9 |
Intestine | 5.7 | 0.5 | 6.3 | 5.1 | 5.4 |
Kidney | 12.3 | 0.5 | 10.3 | 16.1 | 7.1 |
Heart | 14.9 | 0.5 | 11.2 | 21.2 | 11.3 |
Musculoskeletal system | 51.0 | 8.1 | 45.1 | 53.7 | 68.3 |
Nervous system | 6.2 | 1.8 | 5.7 | 5.6 | 10.1 |
Sicca symptoms | 42.0 | 2.3 | 45.5 | 36.9 | 43.4 |
Masticatory organ | 30.3 | 12.4 | 25.3 | 38.6 | 27.5 |