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Table 2 Univariate analysis of the relationship between change in flow-mediated dilatation and GTN-mediated dilatation, features of RA and CV risk factors in 31 patients with early RA

From: Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis

  R2 β coeff P
FMD:    
RF presence - - 0.037
Log CRP level    
At week 0 0.173 -0.946 0.020
At week 52 0.319 -1.700 0.001
ESR    
At week 0 0.142 -1.451 0.037
At week 52 0.001 -0.065 0.91
Change in GMD 0.428 0.487 < 0.001
Carotid IMT at baseline 0.196 -10.22 0.013
Age 0.346 -0.133 < 0.001
Post menopausal status - - 0.002
GMD:    
Log CRP level    
At week 0 0.214 -0.394 0.006
At week 52 0.431 -0.693 < 0.001
Change in FMD 0.428 0.880 < 0.001
Carotid IMT at baseline 0.232 -3.89 0.007
Age 0.206 -0.035 0.012
Pack year history 0.173 -0.148 0.022
Ever smoking - - 0.02
LDL    
At week 0 0.173 -0.561 0.086
At week 52 0.352 -0.552 0.015
  1. Parameters showing statistically significant relationships are included. Bold values are statistically significant.
  2. CRP = C-reactive protein; CV = cardiovascular; ESR = erythrocyte sedimentation rate; FMD = flow-mediated dilatation; GMD = GTN-mediated dilatation; GTN = glyceryl trinitrate; IMT = intima-media thickening; LDL = low-density lipoprotein; RA = rheumatoid arthritis; RF = rheumatoid factor.