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Table 2 Univariate analysis of the relationship between change in flow-mediated dilatation and GTN-mediated dilatation, features of RA and CV risk factors in 31 patients with early RA

From: Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis

 

R2

β coeff

P

FMD:

   

RF presence

-

-

0.037

Log CRP level

   

At week 0

0.173

-0.946

0.020

At week 52

0.319

-1.700

0.001

ESR

   

At week 0

0.142

-1.451

0.037

At week 52

0.001

-0.065

0.91

Change in GMD

0.428

0.487

< 0.001

Carotid IMT at baseline

0.196

-10.22

0.013

Age

0.346

-0.133

< 0.001

Post menopausal status

-

-

0.002

GMD:

   

Log CRP level

   

At week 0

0.214

-0.394

0.006

At week 52

0.431

-0.693

< 0.001

Change in FMD

0.428

0.880

< 0.001

Carotid IMT at baseline

0.232

-3.89

0.007

Age

0.206

-0.035

0.012

Pack year history

0.173

-0.148

0.022

Ever smoking

-

-

0.02

LDL

   

At week 0

0.173

-0.561

0.086

At week 52

0.352

-0.552

0.015

  1. Parameters showing statistically significant relationships are included. Bold values are statistically significant.
  2. CRP = C-reactive protein; CV = cardiovascular; ESR = erythrocyte sedimentation rate; FMD = flow-mediated dilatation; GMD = GTN-mediated dilatation; GTN = glyceryl trinitrate; IMT = intima-media thickening; LDL = low-density lipoprotein; RA = rheumatoid arthritis; RF = rheumatoid factor.
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Arthritis Research & Therapy

ISSN: 1478-6362

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