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Table 1 Demographic and clinical characteristics of study subjects

From: Treating patients with fibromyalgia in primary care settings under routine medical practice: a claim database cost and burden of illness study

Demographics

FMS patients

n = 1,081

Reference group

n = 62,445

Statisticsa

P value

Age in years, mean (SD)

54.2 (10.1)

49.1 (17.9)

16.29

<0.001

   18–44

15.6

45.1

3.09

<0.001

   45–64

71.2

32.9

  

   65–84

13.0

19.8

  

   ≥ 85

0.1

2.2

  

Gender, percentage of females

96.7

53.5

796.02

<0.001

Pensioners, percentage

42.8

31.2

1.46 (1.26–1.70)

<0.001

BMI in kg/m2, mean (SD)

28.6 (5.3)

27.4 (5.1)

7.06

<0,001

Smoking, percentage

18.2

21.0

1.35 (1.15–1.58)

<0.001

Alcoholism, percentage

0.7

1.7

1.55 (0.76–3.16)

0.229

Main comorbiditiesb

Blood hypertension

27.8

21.8

1.37 (1.19–1.59)

<0.001

Dyslipemia

37.0

23.3

1.94 (1.71–2.21)

<0.001

Diabetes mellitus

8.4

9.1

1.09 (0.87–1.36)

0.449

Obesity/weight gain (BMI > 27 kg/m2)

41.1

31.7

1.34 (1.18–1.53)

<0.001

Coronary heart disease

1.8

3.6

1.02 (0.64–1.63)

0.924

Stroke

3.3

4.1

1.38 (0.98–1.95)

0.064

Peripheral vascular disease

4.8

6.9

1.25 (0.94–1.67)

0.131

COPD

0.9

2.8

1.06 (0.56–7.17)

0.855

Asthma

6.1

4.0

1.36 (1.06–1.76)

0.018

Any neurological disorders

0.4

0.5

0.77 (0.28–2.07)

0.601

Dementia

0.4

0.9

0.88 (0.32–2.38)

0.794

Migraine

12.6

3.6

2.41 (1.99–2.92)

<0.001

Major depressive disorders

40.2

10.7

3.85 (3.39–4.37)

<0.001

Anxiety disorders

31.3

19.7

1.24 (1.09–1.42)

0.001

Any disease of the digestive system

70.3

54.0

1.44 (1.24–1.67)

<0.001

Irritable bowel syndrome

5.1

1.2

2.56 (1.91–3.44)

<0.001

GERD

14.2

5.0

2.14 (1.77–2.59)

<0.001

Gastritis

22.4

11.6

1.51 (1.29–1.78)

<0.001

Pain

20.5

5.5

2.94 (2.51–3.43)

<0.001

Neoplasm

4.3

3.5

1.23 (0.91–1.66)

0.187

Morbidity burden

    

   Charlson index, mean (SD)

0.29 (0.62)

0.26 (0.58)

1.71

0.089

   RUB index

    

Low

9.8

27.2

354.8

<0.001

Moderate

76.2

52.3

  

High

9.7

5.7

  

Very high

0.8

0.5

  

Healthy

3.4

14.3

  
  1. aValues of t or chi-square for age, body mass index (BMI), gender, age group, and morbidity burden comparisons; other values are odds ratio adjusted for age and gender with 95% confidence intervals in parentheses. bUnless otherwise indicated, all values are percentages. COPD, chronic obstructive pulmonary disease; FMS, fibromyalgia syndrome; GERD, gastroesophageal reflux disease; RUB, resource utilization band; SD, standard deviation.