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Table 1 99mTc accumulation values obtained at day 4 when no magnet was implanted

From: Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice

 

mBSA + PBS

DXM suspension

Polymer microparticles

SPION suspension

Microparticles + SPIONs

Complete microparticles

 

(-)

(-)

(-)

(-)

(-)

(-)

 

2.01

0.96

1.68

1.48

1.89

1.09

 

2.32

1.33

1.76

1.54

1.23

1.31

 

2.21

1.36

1.33

1.33

2.08

1.09

 

2.31

1.38

1.55

1.65

2.09

1.08

 

2.1

1.31

1.47

1.23

1.85

1.21

Mean

2.19

1.27

1.56

1.45

1.83

1.16

SD

0.13

0.17

0.17

0.17

0.35

0.10

  1. The values are expressed as the ratio of the gamma-counting values in the treated joint (left knee) to those of the untreated joint (right knee). (-) indicates groups without a magnet. DXM, dexamethasone 21-acetate; mBSA, methyl bovine serum albumin; PBS, phosphate-buffered saline; SD, standard deviation; SPION, superparamagnetic iron oxide nanoparticle.
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Arthritis Research & Therapy

ISSN: 1478-6362

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