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Figure 5 | Arthritis Research & Therapy

Figure 5

From: DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Faslpr/lprmice in vivo

Figure 5

Both classes of inhibitory oligonucleotides (INH-ODNs) require CCT and GGG triplets for the full inhibitory activity. AM14 B cells were stimulated with PL2-3 immune complexes. Indicated INH-ODNs and control ODN-4173 (all at a concentration of 1 μg/mL) were added simultaneously. Proliferation was measured. One of two similar experiments is shown.

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Arthritis Research & Therapy

ISSN: 1478-6362

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