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Table 2 Mutational frequencies of B cell subsets in peripheral blood from patients with rheumatoid arthritis

From: Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor

Population Number of Sequences Frequency (number) of mutated sequences Mean (range) number of mutated nucleotides per mutated sequence Overall mutational frequency Mutational frequency for mutated sequences
CD19+ IgD+ CD27- 92 24%a (n = 22) 1.8 bpa (1 to 5 bp) 1.7 × 10-3a 7.3 × 10-3a
CD19+ IgD+ CD27+ 28 96% (n = 27) 12.3 bp (2 to 29 bp) 4.9 × 10-2 5.1 × 10-2
  1. a Significant difference (P < 0.05) between the CD19+ IgD+ CD27 and the CD19+ IgD+ CD27+ subsets.