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Table 2 Flow cytometric analysis of human chondrocytes derived from normal and OA-affected articular cartilage, cultured in monolayer for 24 hours (n = 10) and stained for Stro-1 and Notch-1

From: Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis

    Percentage positive
  Age and gender OA grade† Stro-1 Notch-1
Donor 1 53 male 1 25.1 6.1
Donor 2 17 female 1 9.5 4.3
Donor 3 65 male 1 to 2 nd* 14.0
Donor 4 61 male 2 26.5 2.8
Donor 5 30 male 2 54.6 1.6
Donor 6 56 female 2 29.1 3.4
Donor 7 65 female 2 nd 4.2
Donor 8 64 male 2 to 3 22.7 3.1
Donor 9 59 male 3 to 4 31.0 nd
Donor 10 64 male 3 to 4 5.9 2.5
   Mean ± SE 25.6 ± 5.2 4.7 ± 1.2
  1. † Grade 1 represents intact surface, Grade 2 minimal fibrillation, Grade 3 overt fibrillation and Grade 4 full thickness defect. *nd = not determined; OA = osteoarthritis; SE = standard error.