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Table 4 Change in cartilage thickness (ThCtAB) over one year in participants with and without medial subchondral bone sclerosis at baseline

From: Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiative

  No tibial sclerosis (n = 103) Tibial sclerosis (n = 53) No femoral sclerosis (n = 100) Femoral sclerosis (n = 56)
  MC% SRM P (FUvs.BL) MC% SRM P (FUvs.BL) MC% SRM P (FUvs.BL) MC% SRM P (FUvs.BL)
MT -0.3 -0.13 0.19393 -0.9 -0.22 0.12093 -0.3 -0.11 0.26937 -1.0 -0.24 0.08337
cMF -1.4 -0.23 0.02012 -3.2 -0.46 0.00168 -0.8 -0. 17 0.08584 -4.6 -0.48 0.00064
MFTC -0.9 -0.24 0.01704 -2. 0 -0.46 0.00168 -0.6 -0.19 0.05783 -2.7 -0.48 0.00074
cMT -0.5 -0.14 0.15907 -1.6 -0.29 0.04127 -0.4 -0.12 0.22676 -1.7 -0.31 0.02597
ccMF -2.3 -0.27 0.00678 -4.2 -0.42 0.00369 -1.4 -0.23 0.02596 -6.6 -0.44 0.00171
cMFTC -1.4 -0.27 0.00639 -2.7 -0.46 0.00141 -0.9 -0.24 0.01730 -3.7 -0.47 0.00094
  1. The P value indicates the level of significance for changes between year one follow up (FU) versus baseline (BL) data using a paired t-test.
  2. ccMF = central subregion of the weight bearing medial femoral condyle; cMF = weight bearing medial femoral condyle; cMFTC = central medial femorotibial compartment; cMT = central subregion of the medial tibia; MC% = mean change (in %); MFTC = medial femorotibial compartment; MT = medial tibia; SRM = standardized response mean (mean change/SD of change).