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Table 4 Change in cartilage thickness (ThCtAB) over one year in participants with and without medial subchondral bone sclerosis at baseline

From: Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiative

 

No tibial sclerosis (n = 103)

Tibial sclerosis (n = 53)

No femoral sclerosis (n = 100)

Femoral sclerosis (n = 56)

 

MC%

SRM

P (FUvs.BL)

MC%

SRM

P (FUvs.BL)

MC%

SRM

P (FUvs.BL)

MC%

SRM

P (FUvs.BL)

MT

-0.3

-0.13

0.19393

-0.9

-0.22

0.12093

-0.3

-0.11

0.26937

-1.0

-0.24

0.08337

cMF

-1.4

-0.23

0.02012

-3.2

-0.46

0.00168

-0.8

-0. 17

0.08584

-4.6

-0.48

0.00064

MFTC

-0.9

-0.24

0.01704

-2. 0

-0.46

0.00168

-0.6

-0.19

0.05783

-2.7

-0.48

0.00074

cMT

-0.5

-0.14

0.15907

-1.6

-0.29

0.04127

-0.4

-0.12

0.22676

-1.7

-0.31

0.02597

ccMF

-2.3

-0.27

0.00678

-4.2

-0.42

0.00369

-1.4

-0.23

0.02596

-6.6

-0.44

0.00171

cMFTC

-1.4

-0.27

0.00639

-2.7

-0.46

0.00141

-0.9

-0.24

0.01730

-3.7

-0.47

0.00094

  1. The P value indicates the level of significance for changes between year one follow up (FU) versus baseline (BL) data using a paired t-test.
  2. ccMF = central subregion of the weight bearing medial femoral condyle; cMF = weight bearing medial femoral condyle; cMFTC = central medial femorotibial compartment; cMT = central subregion of the medial tibia; MC% = mean change (in %); MFTC = medial femorotibial compartment; MT = medial tibia; SRM = standardized response mean (mean change/SD of change).
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Arthritis Research & Therapy

ISSN: 1478-6362

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