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Table 1 Magnetic resonance imaging (MRI) erosions predicting subsequent radiographic erosions and MRI bone marrow edema predicting subsequent MRI erosions

From: The utility of MRI in predicting radiographic erosions in the metatarsophalangeal joints of the rheumatoid foot: a prospective longitudinal cohort study

MRI erosions predicting subsequent radiographic erosions
Time interval between studies Patients New x-ray erosions preceded by MRI erosion MRI erosions NOT leading to x-ray erosion New x-ray erosion NOT preceded by MRI erosion Studies not having an x-ray or MRI erosion Sensitivity Specificity PPV NPV Odds ratio
(CI)
6 months 43 3 32 1 430 0.75 0.93 0.086 0.998 a40.3
(4.08–398.7)
12 months 39 3 27 2 417 0.6 0.94 0.10 0.995 a32.2
(3.7–144.6)
24 months 41 3 15 1 218 0.75 0.94 0.17 0.995 a43.6
(4.27–445)
MRI bone marrow edema predicting subsequent MRI erosions
Time interval between studies Patients New MRI erosions preceded by BME BME NOT leading to MRI erosion New MRI erosion NOT preceded by BME Studies not having an MRI erosion or BME Sensitivity Specificity PPV NPV Odds ratio
(CI)
6 months 43 4 12 4 410 0.50 0.97 0.25 0.99 a34.17
(7.62–153.1)
12 months 39 6 6 3 204 0.67 0.97 0.50 0.99 a68.0
(13.6–338.9)
  1. The data for the major endpoints of the study are summarized here. The number of patients at each time interval varies because not all patients completed all studies. All radiographic erosions not preceded by an MRI erosion were preceded by MRI defects. There were only five new radiographic erosions for the entire cohort. aStatistically significant. BME, bone marrow edema; CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value.