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Table 6 Independent predictors of cortical hand bone loss, results from multivariate logistic regression analyses

From: Antibodies to cyclic citrullinated protein and erythrocyte sedimentation rate predict hand bone loss in patients with rheumatoid arthritis of short duration: a longitudinal study

  One-year cortical hand bone loss Two-year cortical hand bone loss Five-year cortical hand bone loss
  OR
(95% CI)
P value OR
(95% CI)
P value OR
(95% CI)
P value
Anti-CCP (> 25 U/ml) 2.2
(1.0 to 4.5)
0.04 2.6
(1.1 to 6.2)
0.03 4.9
(1.4 to 16.7)
0.01
ESR (> 20 mm/h) 4.5
(2.0 to 9.9)
< 0.001 3.5
(1.3 to 9.3)
0.01   
Prednisolone use    4.7
(1.6 to 14.1)
0.006   
Age (years) 1.0
(0.9 to 1.0)
0.62 1.0
(0.9 to 1.1)
0.23 1.1
(1.0 to 1.1)
0.89
Sex (female) 1.0
(0.4 to 2.4)
0.95 0.5
(0.2 to 1.3)
0.14 0.9
(0.2 to 3.4)
0.02
Constant 0.5 0.35 0.4 0.37 0.3 0.31
  1. Final models after multivariate logistic regression analyses. Dependent variable: cortical hand bone loss (yes/no). Anti-CCP = antibodies to cyclic citrullinated peptide; CI = confidence interval; ESR = erythrocyte sedimentation rate; OR = odds ratio.