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Table 1 Proportion of RA and AITDs patients and controls with skewed X-chromosome inactivation

From: Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases

  Number (%) observed with skewed
Degree of skewing (%) RA (n = 76) AITDs (n = 100) Control females (n = 170)
90+ 17 (22.4) 14 (14) 7 (4.1)
80 to 89 9 (11.8) 12 (12) 12 (7.1)
70 to 79 11 (14.5) 23 (23) 29 (17.1)
60 to 69 28 (36.8) 22 (22) 36 (21.2)
50 to 59 11 (14.5) 29 (29) 86 (50.6)
  1. For comparison by chi-squared P < 0.0001 and P = 0.0015 (> 80% skewing); P < 0.0001 and P = 0.0034 (90+% skewing) for patients with rheumatoid arthritis (RA) and autoimmune thyroid diseases (AITDs), respectively.