Skip to main content

Table 2 Characteristics of the patients with rheumatoid arthritis and skewed X-chromosome inactivation

From: Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases

Patient Birth date Disease onset Pregnancy history RF status ACPA status Other autoimmune disease immunosuppressive therapy
90+% skewing        
1 1949 48 G7, P4, A3 + + GSG MXT
2 1954 42 G5, P4, A1 + + - Plaquenil
3 1945 52 G7, P7, A0 - - GSG -
4 1946 40 G3, P2, A1 + - - -
5 1956 30 G2, P2, A0 - - - -
6 1946 40 G3, P2, A1 - + GSG -
7 1945 40 G4, P4, A0 + - - -
8 1945 39 G5, P5, A0 - + - -
9 1941 49 G7, P5, A2 + + - MXT
10 1947 49 G4, P3, A1 + - GSG -
11 1945 58 G4, P2, A1 - + GSG MXT
12 1950 40 G3, P2, A1 + + GSG MXT
13 1943 53 G3, P3, A0 + - - -
14 1961 35 G2, P1, A1 + - - -
15 1937 38 G4, P4, A0 - - - -
16 1941 45 G5, P3, A1 + + - -
17 1947 43 G3, P2, A0 - + GSG -
80 to 89% skewing        
18 1959 42 G5, P5, A0 + + - MXT
19 1940 62 G0, P0, A0 - - - -
20 1938 60 G9, P8, A1 + + GSG MXT
21 1954 27 G0, P0, A0 + + GSG -
22 1957 37 G5, P5, A0 + + GSG -
23 1948 55 G9, P7, A0 + - - MXT
24 1948 55 G0, P0, A0 - - - -
25 1937 50 G3, P2, A1 - + GSG -
26 1985 14 G0, P0, A0 + - - -
  1. A = spontaneous abortions; ACPA = anti-citrullinated protein/peptide antibodies; G = number of pregnancies; GSG = Sjögren's syndrome; MTX = methotrexate; P = para (pregnancies carried to term and delivered); RF = rheumatoid factor.