Figure 4
Effect of ephrin B2 activation of the EphB4 receptor on human osteoarthritic chondrocytes (n = 8) on the gene expression level of (a) IL-1β, (b) IL-6, (c) MMP-1, (d) MMP-2, (e) MMP-9, (f) MMP-13, (g) PAR-2, and (h) collagen type II. Cells were incubated for 18 hours. Data are expressed as the mean ± SEM of arbitrary unit over the control which was attributed a value of 1. Statistical significance was assessed by Student's t-test and P values are versus control.